I'm not missing Bill/Fleur in the least so the less we see of it, the better. Remus/Tonks? Depends on how it's played and how badly Steve Kloves butchers it.

Unfortunately, if you saw what the guy playing Bill looked like in Prisoner of Azkaban, I'm not sure I want to see Bill. Supposedly he was promised the role if they included Bill again -- but he looked like a craggy farm hand, not The Hot Weasley. The Charlie actor was just as bad -- the only thing he had going for him was a resemblance to Chris Rankin. I don't know how the casting people managed to get cute kids for Ginny, Ron and Twins but mangled the two oldest and clearly hottest brothers. Sheesh...